Hello!

I am a postdoc at Lund University. I studied computer science and got my PhD from Sun Yat-sen University. My research focuses on integration of omics and clinical data to study biological changes in neurodegenerative diseases. In my leisure time, I enjoy playing chess and traveling.

Selected publications

^# First or co-first author, ^* Corresponding or co-corresponding author.

Haoyang Zhang, Muhammad Kabir, Mauno Vihinen^*. PON-Del predictor for sequence retaining protein deletions. PLOS Computational Biology. 2026. Journal article First author Code Server

Haoyang Zhang, Xinning Luan, Mauno Vihinen^*. Proteome-wide analysis of human deletions. Proteins. 2026. Journal article First author

Haoyang Zhang, Muhammad Kabir, Saeed Ahmed, Mauno Vihinen^*. There will always be variants of uncertain significance. Analysis of VUSs. NAR Genomics and Bioinformatics. 2024. Journal article First author

Haoyang Zhang^*, Yongping Chen, Liangbin Zhou, Liming Zheng. Letter to the Editor: Is Omeprazole a contributing risk factor for osteoarthritis (OA)?. Journal of Translational Medicine. 2024. Letter First author

Haoyang Zhang^#, Zhenxing Lu^#, Fan Yang, Hongwei Chen, Le Zhang^*, Huiying Zhao^*, Yongkun Chen^*. Symptom profiles and vaccination status for COVID-19 after the adjustment of the dynamic zero-COVID policy in China: an observational study. Journal of Medical Virology. 2023. Journal article First author Code

Haoyang Zhang, Xuehao Xiu, Yuedong Yang^*, Yuanhao Yang^*, Huiying Zhao^*. Identification of putative causal relationships between type 2 diabetes and blood-based biomarkers in East Asians by Mendelian randomization. American Journal of Epidemiology. 2022. Journal article First author

Haoyang Zhang, Xuehao Xiu, Angli Xue, Yuedong Yang^*, Yuanhao Yang^*, Huiying Zhao^*. Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract. International Journal of Epidemiology. 2022. Journal article First author Code

Haoyang Zhang, Junkang Wei, Zifeng Liu, Xun Liu, Yutian Chong, Yutong Lu, Huiying Zhao, Yuedong Yang^*. DGAT-onco: A differential analysis method to detect oncogenes by integrating functional information of mutations. IEEE BIBM. 2021. Conference paper First author Code

Hongwei Chen^#, Bingjie Fan^#, Huiyao Chen^#, Yongkun Chen^*, Yuelong Shu^*, Haoyang Zhang^*. MOCR-DB: The Multi-Omics Causal Resource Database for Genetic Correlation, Causal Inference and Functional Interpretation (Accepted). Phenomics. 2026. Journal article Corresponding author

Ruli Wang^#, Congwei You^#, Zijuan Dong^#, Qingqing Zheng, Xiaowei Zheng, Liangbin Zhou, Xiaolei Wang^*, Le Zhang^*, Haoyang Zhang^*. Wearable Device-Measured Physical Activity and Risk of MAFLD in Adolescents. American Journal of Preventive Cardiology. 2025. Journal article Corresponding author Code

Hongwei Chen^#^*, Danming Yo^#, Liangbin Zhou, Haoyang Zhang^*. Sex differences in the genetic relationship between type 2 diabetes and cataract: Insights from East Asian and European Populations. Medicine Advances. 2025. Journal article Corresponding author

Hongwei Chen^#^*, Mengyuan Hu^#, Huiyao Chen, Juan Yang, Fan Yang, Yahui Li, Zhenzhen Pan, Qiming Pan, Huili Ju, Lihong Zhu, Le Zhang^*, Haoyang Zhang^*. Resilience of Pediatric Healthcare Services in an Urban Hospital in China During the COVID-19 Pandemic in Late 2022. BMJ Paediatrics Open. 2025. Letter Corresponding author Code

Fan Yang^#, Mengyuan Hu^#, Lulian Xu^#, Xiaowei Zheng, Lihong Zhu^*, Le Zhang^*, Haoyang Zhang^*. Potential Alternative and Novel Biomarkers for Paediatric MAFLD: exploratory evidence from a Chinese cohort. BMC Gastroenterology. 2025. Journal article Corresponding author Code

Shen Chen^#, Chun Wan^#, Chao Yu^#, Tianran Shen^#, Haoyang Zhang, Jinghe Xiao, Yiran You, Xinxin Shen, Jie Li, Wenhua Ling, Rong Huang, Hongliang Xue, Xu Chen^*. Dietary anthocyanins alleviates age-dependent hepatic steatosis by expanding Limosilactobacillus reuteri and modulating gut microbiota-bile acid-hepatic FXR signaling. Hepatology. 2026. Journal article Co-author

Siying Lin, Haoyang Zhang, Mengling Qi, David N. Cooper, Yuedong Yang, Yuanhao Yang, Huiying Zhao^*. Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage. 2023. Journal article Co-author

Xu Chen^#, Shen Chen^#, Juan Pang^#, Rong Huang, Yiran You, Haoyang Zhang, Jinghe Xiao, Hongliang Xue, Wenhua Ling^*. Hepatic steatosis aggravates atherosclerosis via small extracellular vesicle-mediated inhibition of cellular cholesterol efflux. Journal of Hepatology. 2023. Journal article Co-author

Xuehao Xiu^#, Haoyang Zhang^#, Angli Xue, David N. Cooper, Li Yan, Yuedong Yang^*, Yuanhao Yang^*, Huiying Zhao^*. Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians. BMC Medicine. 2022. Journal article Co-author

Dan Sun, Yujie Jin, Ting Wang, Kai Zheng, Rocio Rios, Haoyang Zhang, Giovanni Targher, Christopher Byrne, Weiping Yuan, Ming-Hua Zheng^*. MAFLD and risk of CKD. Metabolism. 2021. Journal article Co-author

Maggie Haitian Wang^#^*, Jianpeng Lou^#, Linwei Cao^#, Shiyu Zhao, Renee W. Y. Chan, Paul K. S. Chan, Martin C. W. Chan, Mike K. C. Chong, William K. K. Wu, Yi Wei, Haoyang Zhang, Benny C. Y. Zee, Eng-Kiong Yeoh^*. Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin. Journal of Infection. 2021. Journal article Co-author

Conferences

MOCR-DB: The Multi-Omics Causal Resource Database for Genetic Correlation, Causal Inference and Functional Interpretation Annual Meeting of the China Association for Science and Technology -- Life Omics Big Data and Artificial Intelligence. 2026 Jul. Beijing, China. Poster presentation
pQTL-driven Bayesian Network Reveals Hierarchical Genetic Architecture in CSF Proteomics AAIC (Alzheimer's Association International Conference). 2026 Jul. London, UK. Poster presentation
DGAT-onco: A Differential Analysis Method to Detect Oncogenes by Integrating Functional Information of Mutations IEEE BIBM (IEEE International Conference on Bioinformatics and Biomedicine). 2021 Dec. Virtual. Oral presentation

Grants

Developing a Comprehensive Database for Investigating Genetic Relationships within Phenotypes The Royal Physiographic Society in Lund. 2024–2026.
Unveiling Networked Causality Landscape for Novel Causal Connections (KR2024-0123) The Gyllenstierna Krapperup's Foundation. 2024–2025.

Habits

Xiangqi (Chinese chess) 4th place, Men's Team (EXF with Zihan Qiao and Wong Ho Yee). 4th World Xiangqi Open. 2024 Aug. Dublin, Ireland.