. PON-Del predictor for sequence retaining protein deletions. PLOS Computational Biology. 2026. Journal article First author CodeServer
Hello!
I am a postdoc at Lund University. I studied computer science and got my PhD from Sun Yat-sen University. My research focuses on integration of omics and clinical data to study biological changes in neurodegenerative diseases. My contribution is reflected in citations1512 h-index19.
In my leisure time, I enjoy playing chess and traveling.
Selected publications
# First or co-first author, * Corresponding or co-corresponding author.
. Proteome-wide analysis of human deletions. Proteins. 2026. Journal article First author
. There will always be variants of uncertain significance. Analysis of VUSs. NAR Genomics and Bioinformatics. 2024. Journal article First author
. Letter to the Editor: Is Omeprazole a contributing risk factor for osteoarthritis (OA)?. Journal of Translational Medicine. 2024. Letter First author
. Symptom profiles and vaccination status for COVID-19 after the adjustment of the dynamic zero-COVID policy in China: an observational study. Journal of Medical Virology. 2023. Journal article First author Code
. Identification of putative causal relationships between type 2 diabetes and blood-based biomarkers in East Asians by Mendelian randomization. American Journal of Epidemiology. 2022. Journal article First author
. Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract. International Journal of Epidemiology. 2022. Journal article First author Code
. DGAT-onco: A differential analysis method to detect oncogenes by integrating functional information of mutations. IEEE BIBM. 2021. Conference paper First author Code
. MOCR-DB: The Multi-Omics Causal Resource Database for Genetic Correlation, Causal Inference and Functional Interpretation (Accepted). Phenomics. 2026. Journal article Corresponding author Server
. Wearable Device-Measured Physical Activity and Risk of MAFLD in Adolescents. American Journal of Preventive Cardiology. 2025. Journal article Corresponding author Code
. Sex differences in the genetic relationship between type 2 diabetes and cataract: Insights from East Asian and European Populations. Medicine Advances. 2025. Journal article Corresponding author
. Resilience of Pediatric Healthcare Services in an Urban Hospital in China During the COVID-19 Pandemic in Late 2022. BMJ Paediatrics Open. 2025. Letter Corresponding author Code
. Potential Alternative and Novel Biomarkers for Paediatric MAFLD: exploratory evidence from a Chinese cohort. BMC Gastroenterology. 2025. Journal article Corresponding author Code
. Dietary anthocyanins alleviates age-dependent hepatic steatosis by expanding Limosilactobacillus reuteri and modulating gut microbiota-bile acid-hepatic FXR signaling. Hepatology. 2026. Journal article Co-author
. Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage. 2023. Journal article Co-author
. Hepatic steatosis aggravates atherosclerosis via small extracellular vesicle-mediated inhibition of cellular cholesterol efflux. Journal of Hepatology. 2023. Journal article Co-author
. Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians. BMC Medicine. 2022. Journal article Co-author
. MAFLD and risk of CKD. Metabolism. 2021. Journal article Co-author
. Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin. Journal of Infection. 2021. Journal article Co-author
Conferences
- MOCR-DB: The Multi-Omics Causal Resource Database for Genetic Correlation, Causal Inference and Functional Interpretation Annual Meeting of the China Association for Science and Technology -- Life Omics Big Data and Artificial Intelligence. 2026 Jul. Beijing, China.
- pQTL-driven Bayesian Network Reveals Hierarchical Genetic Architecture in CSF Proteomics AAIC (Alzheimer's Association International Conference). 2026 Jul. London, UK.
- DGAT-onco: A Differential Analysis Method to Detect Oncogenes by Integrating Functional Information of Mutations IEEE BIBM (IEEE International Conference on Bioinformatics and Biomedicine). 2021 Dec. Virtual.
Grants
- Developing a Comprehensive Database for Investigating Genetic Relationships within Phenotypes The Royal Physiographic Society in Lund. 2024–2026.
- Unveiling Networked Causality Landscape for Novel Causal Connections (KR2024-0123) The Gyllenstierna Krapperup's Foundation. 2024–2025.